|
KMID : 0363620080290010001
|
|
Journal of Korean Oriental Medicine
2008 Volume.29 No. 1 p.1 ~ p.6
|
|
|
A Crossover Clinical Trial to Determine the Effect of Siguan(Four Gates) Points on Gastrointestinal Motility Suppressed by Loperamide Administration
|
|
Oh Dal-Seok
Jung So-Young
Kim Ae-Ran
Kang Wee-Chang
Park Ji-Eun
Koo Chang-Mo
Choi Jun-Yong
Jung Hee-Jung
Choi Sun-Mi
Son Chang-Gue
|
|
|
Abstract
|
|
|
Objective: To investigate the therapeutic effect of manual acupuncture at Siguan (four gates, bilateral LI4 and LR3)
on suppression of gastrointestinal motility.
Methods: A single blind, randomized, sham-acupuncture controlled, crossover study was conducted. Twenty healthy male subjects were admitted at hospital, and gastrointestinal motility suppression was induced by loperamide
administration. Just after intake of 20 radio-markers, four gates or sham acupoint treatments were administered every
12 hours, 4 times over 48 hours. Gastrointestinal motility was evaluated by radiographic distribution of the radiomarkers
at stomach or ileum, ascending, transverse, descending colon, sigmoid/rectum, and outside body at serial time points (0, 6, 12, 24, and 48 h).
Results: Four gates acupuncture activated gastrointestinal movement as evidenced by significantly changed distributionof radio-makers at 6, 12, and 48 hours (P < 0.0001, P = 0.001, and P = 0.03, respectively) in Cochran-Mantel-
Haenszel statistics. No serious adverse events occurred in either group.
Conclusions: This study showed a scientific clinical relevance of four gates acupuncture to gastrointestinal
disorders.
|
|
|
KEYWORD
|
|
|
Siguan (four gates), acupuncture, LI4, LR3, gastrointestinal motility
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|